Our group has published a research paper in Molecular Pharmaceutics
Preparing a Dual-Species In Vitro Biofilm Model for Testing Antibiofilm Efficacy
AIM: to develop a dual-species in vitro biofilm model that mimics the infected chronic wound environment, allowing for the efficient analysis of antimicrobial wound dressings. The biofilm was grown on Gel-Gluc, mimicking skin (referred to as artificial skin), using S. aureus, E. coli, and P. aeruginosa in paired combinations. The model’s suitability was validated using previously developed ES fibrous dressings containing chloramphenicol (CAM) and ciprofloxacin (CIP).
The developed dual-species in vitro biofilm model was suitable for the preliminary assessment of the antibacterial efficacy of fibrous wound dressings.
Read more: DOI: 10.1021/acs.molpharmaceut.5c00798